0-60 mph Acceleration Comparison between E 350 and E 450 Trims at Arrowhead

When comparing the E 350 (or E 350 4MATIC®) with the E 450 4MATIC®, the difference in acceleration is immediately apparent. The E 350 and E 350 4MATIC® take approximately 6.1 seconds to accelerate from 0 to 60 mph, offering a solid mid-level performance benchmark. In contrast, the E 450 4MATIC® completes the same sprint in about 4.4 seconds, delivering a markedly more aggressive and sporty feel. From a buyer’s perspective at Arrowhead, the E 450 model’s quicker acceleration could appeal to drivers who prioritize spirited driving and performance, while the E 350 model’s 6.1-second time still offers competent, confident acceleration for everyday driving.

The disparity in acceleration times stems directly from the powertrain differences: the E 450 4MATIC® is tuned for higher output and greater responsiveness, while the E 350 trims are tuned more for balance and efficiency. In real-world driving out of the Arrowhead lot or around Phoenix’s freeway system, that difference means the E 450 4MATIC® will feel significantly more eager in merging and passing situations than the E 350 variants.

Horsepower and Torque Differences for E 350 Trims versus E 450 Trim Levels

The horsepower and torque figures further highlight how Mercedes positions the E 350 and E 450 trims. For the E 350 and E 350 4MATIC®, the output is rated at 255 horsepower and 295 pound-feet of torque. Those numbers reflect a respectable level of performance for a luxury sedan that is meant to balance efficiency, comfort, and everyday usability.

By contrast, the E 450 4MATIC® boosts those figures to 375 horsepower and 369 pound-feet of torque. That represents a substantial increase — nearly a 47% jump in horsepower and almost 25% more torque — which helps explain the much quicker 0–60 time. For a customer visiting Mercedes-Benz of Arrowhead, that extra grunt in the E 450 trim will be felt in sharper throttle response, stronger midrange punch, and a more dynamic driving character at higher speeds.

Hence, while the E 350 trims are well-suited for drivers who want a refined, efficient, and capable sedan, the E 450 4MATIC® is clearly aimed at those who desire performance more in line with a sport-luxury sedan.

Engine Architecture and Drivetrain Configuration across E-Class Trims

Under the hood, the distinctions between the E 350 trims and the E 450 4MATIC® are as meaningful as the performance numbers. The E 350 and E 350 4MATIC® are powered by a 2.0-liter inline-4 turbocharged engine equipped with a mild hybrid drive system. That configuration helps the vehicle balance responsiveness with fuel efficiency, and the mild hybrid assist can support smoother start/stop behavior, torque fill, and a more seamless power curve.

In contrast, the E 450 4MATIC® steps up to a 3.0-liter inline-6 turbocharged engine, also paired with a mild hybrid drive system. The upgrade in displacement and cylinder count gives the E 450 an inherent advantage in power delivery, particularly in higher rev ranges or under load. The mild hybrid system similarly aids in responsiveness and efficiency, helping to cover torque gaps and smooth out transitions.

In terms of drivetrain layout, the base E 350 uses a rear-wheel drive (RWD) setup. That configuration offers classic Mercedes sedan dynamics: a neutral balance, tail-out potential in spirited driving (with traction control intervening), and a driving feel favored by purists. On the other hand, both the E 350 4MATIC® and the E 450 4MATIC® use Mercedes’ 4MATIC® all-wheel drive system, which provides better traction, especially in challenging road or weather conditions. For customers at Mercedes-Benz of Arrowhead, choosing between RWD and 4MATIC® comes down to intended use: if you expect to drive in wet or slippery terrain or want extra all-weather confidence, the 4MATIC® variants may be more attractive; if you prioritize traditional handling feel and slightly lower weight, the RWD E 350 may suffice.